Dimebon ( chemically or the generic term Dimebolin) has attracted a fair amount of attention both in the medical , lay and popular press. The options available for the treatment of Alzheimer’s patients are limited , the disease is so devastating , so that any new therapies or newer therapies that invoke hope are well received.
The problem basically with any new drug , medication or formulations introduced to the marketplace boil down basically to one of numbers and drug interactions. Any medication that is released to the marketplace is basically and essentially only tested on a relatively very small group of patients / victims.
Its not that the testing process is slipshod. It is not and is well is very expensive. Its just that the numbers are relatively small in limited situations. The first thing that is always tested for is safety. If the drug is inherently unsafe then the whole process should be stopped. This potentially does not come into play if the drug will save some people in a situation where nothing else will. Everything in life of course , always comes to risks vs benefits.
The basic problem with drug testing and introduction is simply a matter of numbers , percentages , and interactions with medications or other agents not thought of , or not tested.
It all boils down to statistics and numbers. 1/100 of a percent involving a trial with 100 or even 1000 patients may not uncover damming side effects whereas if that same product is released into the marketplace , with millions of users and patients , and whammo that terrible side effect comes to light now . Not only that when multiplied out , the amount of patients affected adversely is not small , and is indeed large and troubling. The question will be why these interactions and side effects not found , noticed or detected before ?
Which brings up to the beauty of this specific chemical / medication to be used in the treatment of Alzheimer’s Disease.
Dimebon or Dimbolin is an older antihistamine drug which was used in Russia / U.S.S.R. as a widely available medication that was used in great numbers and prevalence for a good period of time. The drug was widely used as it was available easily and widespread without even a prescription. There do not appear to have enough problems with the medication that many problems seem to have be reported with its use.
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dimebon is cure of alzheimer?s disease? – recently dimebolin has sparked renewed interest after being shown to have positive effects on people suffering from alzheimer?s disease. animal studies showing the potential beneficial effects on alzheimer?s disease models were … comfort for the afflicted – for example, the antihistamine dimebolin hydrochloride preserved cognition in an 18-month investigation. and the antimalarial methylthioninium chloride interfered with the accumulation of tau tangles in the brain in an 84-week study. … Pfizer pays $725 Million for experimental drug (Life, Liberty, and … – Pfizer said that it was acquiring the rights to a new experimental substance aimed to help Alzheimer’s disease. The substance (Pictured Above) is Dimebolin, a antihistamine that works on the AMPA/NMDA receptors. … |
http://www.dimebonalzheimers.com
